HitPredict

Interactor 1: MPDZ (O55164)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: 5HT2C (P08909)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: Htr2c

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11150294
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2054 Rn			1 460
+	Hs
		280022 MPDZ_HUMAN (1-2054): 0: 1218: 84.26		5HT2C_HUMAN (1-460): 1.32e-99: 307: 88.04
+	Hs
		280021 MPDZ_HUMAN (1-2054): 0: 1218: 84.26		5HT2A_HUMAN (14-460): 1.04e-83: 267: 48.33
+	Hs
		280029 MPDZ_HUMAN (1-2054): 0: 1218: 84.26		5HT2B_HUMAN (28-403): 2.4e-72: 237: 44.44
+	Hs
		280028 MPDZ_HUMAN (1-2054): 0: 1218: 84.26		DRD3_HUMAN (26-387): 1.43e-70: 230: 26.23
+	Hs
		658221 DLG4_HUMAN (325-465): 3.56e-20: 99.8: 22.54		5HT2C_HUMAN (1-460): 1.32e-99: 307: 88.04
+	Hs
		441654 MAGI2_HUMAN (1675-2053): 5.95e-26: 119: 16.19		ADRB1_HUMAN (31-411): 4.47e-78: 252: 26.48
+	Hs
		441656 MAGI1_HUMAN (2-375): 1.1e-25: 118: 15.78		ADRB1_HUMAN (31-411): 4.47e-78: 252: 26.48
+	Mm
		578603 MAGI3_MOUSE (2-587): 3.34e-24: 113: 12.50		ADRB2_MOUSE (33-459): 4.46e-80: 256: 25.58
+	Hs
		600726 DLG4_HUMAN (325-465): 3.56e-20: 99.8: 22.54		DRD1_HUMAN (52-400): 6.53e-85: 269: 27.75
+	Hs
		656994 DLG4_HUMAN (325-465): 3.56e-20: 99.8: 22.54		5HT2A_HUMAN (14-460): 1.04e-83: 267: 48.33
+	Hs
		429068 MAGI3_HUMAN (2-665): 8.75e-24: 112: 13.48		ADRB2_HUMAN (33-459): 4.5e-79: 253: 24.48
+	Hs
		441653 MAGI3_HUMAN (2-665): 8.75e-24: 112: 13.48		ADRB1_HUMAN (31-411): 4.47e-78: 252: 26.48
+	Hs
		441650 DLG4_HUMAN (325-465): 3.56e-20: 99.8: 22.54		ADRB1_HUMAN (31-411): 4.47e-78: 252: 26.48
+	Mm
		676813 DLG2_MOUSE (3-407): 1.68e-27: 123: 13.26		SSR1_MOUSE (36-422): 1.24e-69: 228: 21.63
+	Mm
		830268 DLG2_MOUSE (3-407): 1.68e-27: 123: 13.26		SSR4_MOUSE (9-446): 1.16e-69: 228: 18.24
+	Rn
		495779 DLG4_RAT (325-465): 3.27e-20: 99.8: 22.54		ADRB2_RAT (33-459): 9.2e-78: 250: 24.89
+	Hs
		722923 NHRF3_HUMAN (994-1449): 5.47e-25: 113: 16.18		SSR5_HUMAN (8-403): 8.8e-72: 233: 19.10
+	Mm
		676812 DLG4_MOUSE (325-465): 3.41e-20: 99.8: 22.54		SSR1_MOUSE (36-422): 1.24e-69: 228: 21.63
+	Rn
		677498 DLG4_RAT (325-465): 3.27e-20: 99.8: 22.54		SSR4_RAT (24-446): 1.19e-69: 228: 17.95
+	Mm
		676818 DLG4_MOUSE (325-465): 3.41e-20: 99.8: 22.54		SSR2_MOUSE (13-417): 9.55e-67: 220: 18.49