Interactor 1: SPT5H (O55201)
Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit)
Gene: Supt5h

Interactor 2: SPT4A (P63271)
Transcription elongation factor SPT4-A (DRB sensitivity-inducing factor small subunit 1) (DSIF small subunit 1) (Transcription elongation factor SPT4 1)
Gene: Supt4h1a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20211142
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KOW~Spt4, Spt4~Spt5-NGN
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0006368 - transcription elongation by RNA polymerase II
GO:0032044 - DSIF complex
GO:0032786 - positive regulation of DNA-templated transcription, elongation
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1082
Mm

1 117
+ Hs
+ Dm
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024