HitPredict

Interactor 1: PSA7 (O59770)
Probable proteasome subunit alpha type-7
Gene: pre10

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20133687
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 253 Sp			1 259
+	Sc
		597248 PSA7_YEAST (1-244): 1.72e-108: 316: 55.02		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Sc
		597214 PSA7_YEAST (1-244): 1.72e-108: 316: 55.02		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Sp
		1013784 PSA5_SCHPO (1-240): 1.24e-95: 282: 30.36		PSA4_SCHPO (1-259): 2.44e-102: 299: 100.00
+	Hs
		156224 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637316 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Dm
		1278639 PSA3_DROME (1-248): 2.13e-99: 292: 42.40		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Hs
		637631 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		637719 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSMA8_HUMAN (2-230): 1.66e-93: 277: 52.74
+	Hs
		156230 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Dm
		611656 PSA3_DROME (1-248): 2.13e-99: 292: 42.40		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Hs
		637325 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		637663 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Ss
		94704 F2Z5K2_PIG (1-237): 1.45e-95: 281: 30.45		F2Z5L7_PIG (2-259): 1.01e-93: 278: 27.27
+	Hs
		656149 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		656276 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSMA8_HUMAN (2-230): 1.66e-93: 277: 52.74
+	Dm
		611647 PSA5_DROME (1-238): 4.48e-95: 280: 29.68		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Hs
		656189 PSA5_HUMAN (1-237): 1.45e-95: 281: 30.45		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Dm
		771311 PSA3_DROME (1-248): 2.13e-99: 292: 42.40		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Hs
		637624 PSA2_HUMAN (6-238): 8.16e-100: 292: 31.62		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10