Interactor 1: HIM1 (O59836)
Hsk1-interacting molecule 1 (DNA repair protein rad35)
Gene: HIM1

Interactor 2: HSK1 (P50582)
Cell cycle serine/threonine-protein kinase hsk1 (EC 2.7.11.1) (Cdc7-related kinase) (Minichromosome maintenance protein kinase)
Gene: HSK1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 12604790, 11402029, 10411894, 10409743, 9705352, 12052858, 34608864, 20230746
Identification Methods pull down, affinity chromatography technology, enzymatic study, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-DBF
Common GO terms GO:0005634 - nucleus
GO:0031431 - Dbf4-dependent protein kinase complex
GO:0033314 - mitotic DNA replication checkpoint signaling
GO:0045739 - positive regulation of DNA repair
GO:1903468 - positive regulation of DNA replication initiation
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 545
Sp

1 507
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024