Interactor 1: CLR4 (O60016)
Histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.355) (EC 2.1.1.366) (EC 2.1.1.367) (Cryptic loci regulator 4) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (HKMT) (Lysine N-methyltransferase 1) (Protein lysine methyltransferase clr4) (PKMT)
Gene: CLR4

Interactor 2: SWI6 (P40381)
Chromatin-associated protein swi6
Gene: SWI6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 21224386, 28143796
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo
Common GO terms GO:0005634 - nucleus
GO:0005721 - pericentric heterochromatin
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031934 - mating-type region heterochromatin
GO:0090053 - positive regulation of pericentric heterochromatin formation
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 490
Sp

1 328
+ Sp
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024