Interactor 1: TOP3 (O60126)
DNA topoisomerase 3 (EC 5.6.2.1) (DNA topoisomerase III)
Gene: TOP3

Interactor 2: HUS2 (Q09811)
ATP-dependent DNA helicase hus2/rqh1 (EC 5.6.2.4) (DNA 3'-5' helicase Rqh1)
Gene: rqh1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12724426, 15702347
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Toprim
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006301 - postreplication repair
GO:0031422 - RecQ family helicase-topoisomerase III complex
GO:0035861 - site of double-strand break
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 622
Sp

1 1328
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Ce
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024