HitPredict

Interactor 1: RAD21 (O60216)
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]
Gene: RAD21

Interactor 2: PDS5A (Q29RF7)
Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112)
Gene: PDS5A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 31010829, 17113138, 17112726, 15855230, 26496610, 28514442, 33961781, 22145905
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
and 2 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 631
Hs

1 1337
+ Mm
+ Xl
+ Xl
+ Hs
+ Xl
+ Xl
+ Dm
+ Sp
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024