Interactor 1: RAD21 (O60216)
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]
Gene: RAD21

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36373674
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007059 - chromosome segregation
GO:0051301 - cell division
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 631
Hs

1 1101
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Xl
+ Xl
+ Mm
+ Dm
+ Mm
+ Sc
+ Hs
+ Sp
+ Sc
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024