HitPredict

Interactor 1: RAD21 (O60216)
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]
Gene: RAD21

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 336
+	Hs
		224414 RAD21_HUMAN (1-631): 0: 696: 100.00		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		224498 RAD21_HUMAN (1-631): 0: 696: 100.00		TRI43_HUMAN (45-303): 1.25e-47: 168: 13.11
+	Hs
		224334 RAD21_HUMAN (1-631): 0: 696: 100.00		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Dm
		332165 O96689_DROME (1-630): 3.72e-175: 516: 34.92		PSC_DROME (3-336): 2.34e-33: 132: 17.31
+	Dm
		332176 O96689_DROME (1-630): 3.72e-175: 516: 34.92		RING1_DROME (208-333): 2.07e-19: 90.5: 41.35