Interactor 1: RAD21 (O60216)
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]
Gene: RAD21
Interactor 2: SMC3 (Q9UQE7)
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)
Gene: SMC3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 28514442, 31010829, 24981860, 33961781, 35271311, 37071682, 20818333, 22145905, 21043528, 15737063, 17113138, 17349791, 15855230, 10931856, 21880767, 16802858, 21111234, 22885700, 18235444 and 1 others
more... |
| Identification Methods | affinity chromatography technology, cross-linking study, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, cosedimentation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N |
| Common GO terms | GO:0000775 - chromosome, centromeric region GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
