HitPredict

Interactor 1: KALRN (O60229)
Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)
Gene: KALRN

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	17043677, unassigned1973
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2986 Hs			1 802
+	Hs
		279887 TRIO_HUMAN (23-2982): 0: 1941: 59.82		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1045493 SPTN1_HUMAN (60-1728): 1.93e-87: 323: 13.27		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		963400 SPTB2_HUMAN (50-1615): 2.89e-77: 289: 12.00		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		974135 DYST_HUMAN (180-1107): 2.38e-15: 85.8: 11.45		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1303862 MACF1_HUMAN (18-548): 1.25e-13: 80.1: 11.71		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		486891 SPTB2_HUMAN (50-1615): 2.89e-77: 289: 12.00		MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51
+	Hs
		486785 SPTN1_HUMAN (60-1728): 1.93e-87: 323: 13.27		MYB_HUMAN (398-727): 5.82e-27: 119: 12.06
+	Hs
		360606 SPTA1_HUMAN (843-1251): 6.32e-31: 136: 12.47		MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51