Interactor 1: DHX16 (O60231)
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16)
Gene: DHX16

Interactor 2: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 35263596
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~RIG-I_C, DEAD~RIG-I_C-RD, DEAD~HA2, HA2~Helicase_C, Helicase_C~Helicase_C, Helicase_C~RIG-I_C, Helicase_C~RIG-I_C-RD, Helicase_C~OB_NTP_bind
Common GO terms GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0016887 - ATP hydrolysis activity
GO:0038187 - pattern recognition receptor activity
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1041
Hs

1 925
+ Hs
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+ Hs
+ Sc
+ Sc
+ Ce
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+ Sc
+ Sc

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Last updated: 15 Jul 2024