HitPredict

Interactor 1: MYPT2 (O60237)
Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)
Gene: PPP1R12B

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030018 - Z disc
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 982 Hs			1 781
+	Hs
		717002 ANK2_HUMAN (38-320): 2.2e-60: 228: 21.58		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717038 ANK3_HUMAN (7-505): 1.1e-57: 220: 14.13		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717358 TANC2_HUMAN (13-880): 2.73e-35: 148: 12.43		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		161316 MYPT1_HUMAN (2-131): 3.19e-16: 86: 18.07		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542282 ANK2_HUMAN (38-320): 2.2e-60: 228: 21.58		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		310037 TNKS1_HUMAN (77-182): 3.24e-09: 63.2: 33.02		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Ce
		105093 G5ECD7_CAEEL (18-981): 1.1e-97: 334: 22.68		BAR1_CAEEL (129-740): 4.72e-102: 334: 24.15
+	Hs
		119768 ANK3_HUMAN (7-505): 1.1e-57: 220: 14.13		ARVC_HUMAN (202-771): 5.66e-94: 316: 18.66
+	Ce
		105092 G5ECD7_CAEEL (18-981): 1.1e-97: 334: 22.68		WRM1_CAEEL (288-457): 3.46e-37: 151: 29.07
+	Hs
		853553 RIPK4_HUMAN (21-365): 7.55e-66: 239: 21.07		IMA5_HUMAN (240-678): 2.52e-65: 228: 16.44
+	Hs
		853707 Q9H4D1_HUMAN (21-365): 2.96e-65: 237: 21.07		IMA5_HUMAN (240-678): 2.52e-65: 228: 16.44
+	Ce
		107984 G5EG29_CAEEL (2-156): 1.53e-10: 67.5: 14.14		WRM1_CAEEL (288-457): 3.46e-37: 151: 29.07