HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 537
+	Hs
		225326 MED14_HUMAN (1-1454): 0: 1560: 100.00		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56
+	Hs
		523092 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		522749 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		411844 TB182_HUMAN (945-1135): 6.75e-20: 99.2: 18.33		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		297808 K0754_HUMAN (1071-1454): 6.75e-24: 112: 11.54		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		433989 TB182_HUMAN (945-1135): 6.75e-20: 99.2: 18.33		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		442866 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		HCK_HUMAN (1-535): 0: 548: 56.64
+	Hs
		411582 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		433930 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		433560 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		LYN_HUMAN (1-535): 0: 535: 54.48
+	Mm
		101424 F8VPR5_MOUSE (836-1217): 4.53e-09: 63.8: 7.75		LYN_MOUSE (1-535): 0: 535: 53.92
+	Hs
		337335 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56