HitPredict

Interactor 1: PCDH7 (O60245)
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)
Gene: PCDH7

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1069 Hs			1 802
+	Hs
		225492 PCDH7_HUMAN (1-1069): 0: 909: 100.00		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		225477 PCDH7_HUMAN (1-1069): 0: 909: 100.00		RET_HUMAN (221-802): 2.33e-148: 465: 34.72
+	Hs
		508294 PCDB7_HUMAN (317-876): 3.84e-118: 384: 26.80		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		872600 PCDG6_HUMAN (230-915): 2.09e-159: 497: 27.17		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872551 PCD20_HUMAN (26-903): 1.05e-118: 390: 31.92		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		508295 PCDA8_HUMAN (647-1068): 7.34e-45: 177: 13.85		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		872601 PCDG5_HUMAN (3-527): 1.35e-89: 310: 20.86		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872599 PCDG7_HUMAN (3-527): 7.62e-89: 308: 21.38		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872592 PCDAC_HUMAN (541-869): 2.42e-52: 201: 22.29		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872603 PCDC2_HUMAN (356-839): 3.21e-45: 179: 31.23		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872602 PCDA8_HUMAN (647-1068): 7.34e-45: 177: 13.85		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		434195 FAT1_HUMAN (534-1069): 1.15e-53: 208: 17.30		RET_HUMAN (221-802): 2.33e-148: 465: 34.72
+	Hs
		872598 PCDB3_HUMAN (582-837): 1.91e-17: 89.7: 27.04		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		385714 PCDGK_HUMAN (582-864): 5.88e-18: 91.7: 28.24		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		385795 PCDB3_HUMAN (582-837): 1.91e-17: 89.7: 27.04		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		674578 PCDB3_HUMAN (582-837): 1.91e-17: 89.7: 27.04		UFO_HUMAN (5-793): 5.98e-159: 486: 22.59
+	Hs
		434321 PCDGH_HUMAN (852-1064): 2.17e-11: 70.5: 5.43		RET_HUMAN (221-802): 2.33e-148: 465: 34.72
+	Hs
		729394 PCDGD_HUMAN (540-1023): 3.82e-54: 206: 21.72		VGFR3_HUMAN (153-356): 9.15e-11: 67.8: 18.78