HitPredict

Interactor 1: SOX15 (O60248)
Transcription factor SOX-15 (Protein SOX-12) (Protein SOX-20) (SRY-box transcription factor 15)
Gene: SOX15

Interactor 2: ATX1L (P0C7T5)
Ataxin-1-like (Brother of ataxin-1) (Brother of ATXN1)
Gene: ATXN1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0007420 - brain development
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 689
+	Hs
		473491 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		ATX1L_HUMAN (1-689): 0: 1204: 100.00
+	Hs
		473479 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		ATX1L_HUMAN (1-689): 0: 1204: 100.00
+	Hs
		473484 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		ATX1L_HUMAN (1-689): 0: 1204: 100.00
+	Hs
		473480 SOX6_HUMAN (24-222): 2.2e-30: 120: 25.63		ATX1L_HUMAN (1-689): 0: 1204: 100.00
+	Hs
		473560 SOX17_HUMAN (46-229): 8.91e-31: 118: 36.02		ATX1L_HUMAN (1-689): 0: 1204: 100.00
+	Dm
		1098061 DICH_DROME (45-207): 5.58e-28: 111: 44.79		Q9W3V7_DROME (467-580): 5.06e-61: 205: 45.61
+	Hs
		817830 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		ATX1_HUMAN (1-190): 6.32e-09: 61.3: 32.46
+	Hs
		313693 SOX14_HUMAN (44-217): 3.38e-30: 113: 41.76		ATX1_HUMAN (1-190): 6.32e-09: 61.3: 32.46
+	Hs
		782194 SOX3_HUMAN (44-230): 2.46e-28: 112: 41.05		ATX1_HUMAN (1-190): 6.32e-09: 61.3: 32.46