HitPredict

Interactor 1: SOX15 (O60248)
Transcription factor SOX-15 (Protein SOX-12) (Protein SOX-20) (SRY-box transcription factor 15)
Gene: SOX15

Interactor 2: NCOA3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1)
Gene: NCOA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 1424
+	Hs
		881838 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		818854 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		818674 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		727952 SOX6_HUMAN (24-222): 2.2e-30: 120: 25.63		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		1332336 SOX17_HUMAN (46-229): 8.91e-31: 118: 36.02		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		225746 SOX15_HUMAN (1-233): 8.57e-47: 156: 100.00		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		881806 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		996797 SSRP1_HUMAN (27-215): 4.69e-31: 122: 13.76		BMAL2_HUMAN (10-541): 1.06e-108: 360: 16.06
+	Hs
		881827 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		EPAS1_HUMAN (12-878): 3.88e-100: 343: 13.27
+	Hs
		818079 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		126174 HM20A_HUMAN (8-209): 3.14e-32: 121: 15.35		BMAL1_HUMAN (6-541): 4.9e-105: 349: 18.23
+	Hs
		727872 SOX6_HUMAN (24-222): 2.2e-30: 120: 25.63		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		1075391 SOX17_HUMAN (46-229): 8.91e-31: 118: 36.02		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		181503 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		CLOCK_HUMAN (1-791): 2.47e-78: 279: 13.73
+	Hs
		181564 HM20A_HUMAN (8-209): 3.14e-32: 121: 15.35		CLOCK_HUMAN (1-791): 2.47e-78: 279: 13.73
+	Hs
		649066 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		ARNT_HUMAN (6-642): 2.95e-76: 272: 16.01
+	Hs
		649051 SOX6_HUMAN (24-222): 2.2e-30: 120: 25.63		ARNT_HUMAN (6-642): 2.95e-76: 272: 16.01
+	Hs
		818819 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87
+	Hs
		818266 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87
+	Hs
		1243843 SOX17_HUMAN (46-229): 8.91e-31: 118: 36.02		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87