HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: KTNA1 (O75449)
Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin)
Gene: KATNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 491
+	Hs
		226044 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		VPS4B_HUMAN (153-489): 4.43e-117: 353: 37.86
+	Hs
		229057 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		VPS4A_HUMAN (153-489): 7.82e-117: 352: 38.30
+	Hs
		226693 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRS7_HUMAN (30-475): 7.06e-109: 331: 25.22
+	Hs
		265448 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KTNA1_HUMAN (1-491): 3.82e-156: 454: 100.00
+	Hs
		226980 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	Hs
		228067 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		AFG2A_HUMAN (201-476): 8.86e-70: 240: 34.29
+	Hs
		875476 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	Hs
		312526 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	Sc
		477159 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		CDC48_YEAST (189-476): 6.52e-80: 267: 39.38
+	Hs
		474971 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	Hs
		475422 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRS7_HUMAN (30-475): 7.06e-109: 331: 25.22
+	At
		1092219 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CD48E_ARATH (1-476): 2.12e-82: 273: 24.79
+	Hs
		476034 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KATL2_HUMAN (189-490): 4.79e-84: 271: 47.76
+	At
		870955 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CD48A_ARATH (1-476): 2.46e-82: 273: 25.00
+	Hs
		875357 RN19A_HUMAN (236-452): 6.6e-31: 128: 21.62		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	At
		1092294 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CD48D_ARATH (191-476): 1.03e-80: 269: 35.64
+	Mm
		841457 RN19A_MOUSE (236-452): 2.59e-30: 126: 21.62		TERA_MOUSE (15-476): 2.39e-79: 265: 26.28
+	Hs
		475529 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		TERA_HUMAN (15-476): 2.39e-79: 265: 26.28
+	Hs
		87546 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		C9JUP7_HUMAN (190-476): 6.86e-80: 265: 37.24
+	Zm
		45033 Q41754_MAIZE (1-76): 8.11e-30: 121: 31.58		A0A1D6QEJ7_MAIZE (196-489): 1.49e-59: 213: 43.09