HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 25959826, 32929329, 35509820, 35256949, 24244333
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0031072 - heat shock protein binding
GO:0031625 - ubiquitin protein ligase binding
GO:0050821 - protein stabilization
GO:0051087 - protein-folding chaperone binding
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 465
Hs

1 211
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024