HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RSSA (P08865)
Small ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4)
Gene: RPSA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.682

Property	Details
Experiments	32929329, 35509820, 35256949, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 295
+	Hs
		229133 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RT02_HUMAN (6-218): 2.67e-83: 254: 21.43
+	Hs
		312452 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RSSA_HUMAN (1-295): 2.16e-153: 432: 100.00
+	At
		1091767 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RSSA2_ARATH (6-288): 2.23e-120: 347: 49.12
+	At
		996193 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RSSA1_ARATH (2-276): 2.64e-117: 340: 51.08
+	Hs
		476611 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RT02_HUMAN (6-218): 2.67e-83: 254: 21.43