HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ODP2 (P10515)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
Gene: DLAT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 647
+	Hs
		489774 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		ODP2_HUMAN (1-647): 0: 672: 100.00
+	Hs
		226705 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ODO2_HUMAN (16-163): 1.19e-25: 112: 20.95
+	Hs
		226358 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ODB2_HUMAN (84-213): 9.1e-13: 72.9: 17.65
+	Sc
		477093 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		ODP2_YEAST (59-231): 2.39e-31: 129: 33.88
+	Hs
		312504 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ODO2_HUMAN (16-163): 1.19e-25: 112: 20.95
+	Hs
		506044 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		ODB2_HUMAN (84-213): 9.1e-13: 72.9: 17.65
+	Hs
		475427 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ODO2_HUMAN (16-163): 1.19e-25: 112: 20.95