HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RFX1 (P22670)
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)
Gene: RFX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 979
+	Hs
		227846 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RFX8_HUMAN (422-959): 8.47e-138: 427: 24.13
+	Hs
		227898 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAVS_HUMAN (4-411): 1.02e-33: 139: 17.81
+	Hs
		227885 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MICA3_HUMAN (10-591): 8.73e-28: 124: 10.07
+	Hs
		226957 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SC24C_HUMAN (8-469): 4.1e-16: 85.6: 13.14
+	Hs
		228101 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KMT2C_HUMAN (111-593): 1.23e-10: 68.2: 8.07
+	Hs
		228767 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAGE1_HUMAN (96-456): 1.03e-10: 67.9: 10.47
+	Mm
		88466 PRKN_MOUSE (1-465): 6.53e-131: 388: 83.66		D3Z656_MOUSE (3-400): 3.69e-15: 82.9: 16.91
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (41-605): 4.23e-09: 63.2: 8.60
+	Rn
		94376 HOIL1_RAT (12-448): 8.73e-66: 221: 17.05		F1M9G7_RAT (2-321): 7.7e-09: 62.1: 13.75
+	At
		1091778 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC31B_ARATH (15-253): 2.51e-23: 109: 19.42
+	At
		1092118 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LIE8_ARATH (43-604): 3.99e-15: 82.5: 9.03
+	Hs
		475943 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OTOG_HUMAN (225-602): 4.57e-13: 75.9: 9.46