Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ARBK2 (P35626)
G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2)
Gene: GRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35509820
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~ubiquitin
Common GO terms GO:0001664 - G protein-coupled receptor binding
GO:0005829 - cytosol
GO:0098793 - presynapse
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 465
Hs

1 688
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024