HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: CRKL (P46109)
Crk-like protein
Gene: CRKL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35987950
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_1~ubiquitin
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0010629 - negative regulation of gene expression
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 465
Hs

1 303
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024