HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ANM2 (P55345)
Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2)
Gene: PRMT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 433
+	Hs
		228488 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM1_HUMAN (85-421): 5.54e-148: 427: 32.84
+	Hs
		226006 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM3_HUMAN (92-421): 1.93e-125: 375: 35.35
+	Hs
		227951 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CARM1_HUMAN (81-429): 1.55e-118: 360: 32.49
+	Hs
		474972 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		ANM2_HUMAN (1-433): 0: 548: 100.00
+	Hs
		153503 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANM5_HUMAN (85-428): 7.45e-102: 318: 20.45
+	Hs
		153518 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ANM5_HUMAN (85-428): 7.45e-102: 318: 20.45
+	At
		1091739 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ANM13_ARATH (10-429): 1.51e-135: 401: 28.44
+	Hs
		153545 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ANM5_HUMAN (85-428): 7.45e-102: 318: 20.45
+	Hs
		476454 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ANM7_HUMAN (116-378): 1.72e-12: 71.2: 23.86