HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 322
+	Hs
		228276 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		228868 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49
+	Hs
		228315 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22
+	Hs
		226765 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35
+	Hs
		878269 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00
+	Hs
		227540 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61
+	Hs
		152845 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		APAF_HUMAN (12-134): 4.76e-11: 65.9: 21.71
+	Hs
		227054 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67
+	Hs
		226098 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIAO1_HUMAN (12-93): 1.73e-09: 60: 28.09
+	Hs
		228326 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SEH1_HUMAN (15-180): 2.01e-09: 60: 18.75
+	Hs
		1281514 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		1219356 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22
+	At
		248908 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC13B_ARATH (54-320): 3.18e-47: 162: 24.82
+	Sc
		477447 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		CIAO1_YEAST (7-198): 9.65e-16: 78.6: 21.00
+	At
		1092369 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC13A_ARATH (54-320): 4.32e-46: 159: 23.40
+	Hs
		476151 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		476181 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22
+	Hs
		475563 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67
+	Hs
		282808 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIAO1_HUMAN (12-93): 1.73e-09: 60: 28.09
+	At
		187391 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		O22826_ARATH (249-321): 6.73e-10: 61.3: 15.07