HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: UBS3A (P57075)
Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1)
Gene: UBASH3A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 35256949, 17599067, 32814053
Identification Methods affinity chromatography technology, pull down, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_9~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016607 - nuclear speck
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 465
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024