HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: TRA2B (P62995)
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)
Gene: TRA2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 288
+	Hs
		227385 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Hs
		228873 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM22_HUMAN (2-287): 6.71e-33: 126: 15.91
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (109-203): 7.23e-23: 99: 30.53
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (109-246): 4.69e-22: 97.6: 21.28
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (109-246): 1.1e-19: 90.7: 19.86
+	Hs
		227193 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIAR_HUMAN (73-272): 5.47e-20: 90.6: 14.00
+	Hs
		227450 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83
+	Hs
		226635 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIA1_HUMAN (113-248): 8.75e-18: 84.1: 18.42
+	Hs
		227415 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRPD_HUMAN (106-178): 6.05e-11: 64: 26.03
+	Hs
		227414 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIRBP_HUMAN (120-192): 7.93e-11: 61.6: 57.53
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (109-246): 4.69e-22: 97.6: 21.28
+	Hs
		312562 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99
+	Hs
		312605 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83
+	Hs
		312493 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TIA1_HUMAN (113-248): 8.75e-18: 84.1: 18.42
+	Hs
		312603 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRPD_HUMAN (106-178): 6.05e-11: 64: 26.03
+	Hs
		312602 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		CIRBP_HUMAN (120-192): 7.93e-11: 61.6: 57.53
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (109-246): 4.69e-22: 97.6: 21.28
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99