HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: 2ABA (P63151)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)
Gene: PPP2R2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 447
+	Hs
		227748 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		2ABD_HUMAN (8-447): 0: 829: 88.86
+	Hs
		227178 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		2ABB_HUMAN (26-447): 0: 798: 89.10
+	Hs
		229114 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		2ABG_HUMAN (25-447): 0: 783: 84.63
+	Hs
		475906 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		2ABD_HUMAN (8-447): 0: 829: 88.86
+	At
		1091660 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		2ABB_ARATH (2-442): 0: 723: 50.00
+	At
		1091630 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		2ABA_ARATH (2-442): 0: 694: 47.71