HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 282
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77
+	Hs
		227110 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		228166 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PPIL4_HUMAN (117-195): 7.73e-27: 110: 39.24
+	Hs
		227193 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIAR_HUMAN (113-209): 9.67e-20: 89.4: 20.62
+	Hs
		226635 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Hs
		227414 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		312562 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		312493 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Hs
		312602 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	At
		975638 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RBG8_ARATH (122-195): 1.46e-27: 106: 40.54
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (92-267): 1.38e-19: 90.2: 18.44
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (117-260): 1.8e-18: 87.1: 22.45
+	Hs
		475739 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90