HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	35509820, 35987950, 35256949
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0098793 - presynapse
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1630
+	Hs
		227141 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	At
		1092049 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		FLS2_ARATH (8-621): 1.42e-111: 385: 21.36
+	Hs
		228731 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRC40_HUMAN (13-349): 4.8e-21: 101: 25.80
+	Hs
		228402 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LRRC7_HUMAN (804-949): 2.35e-11: 71.2: 25.16