HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 4646
+	Hs
		1051604 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		DYHC1_HUMAN (1-4646): 0: 4190: 100.00
+	Hs
		228906 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH9_HUMAN (144-4645): 0: 3735: 23.53
+	Hs
		228317 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH11_HUMAN (62-4645): 0: 3702: 22.89
+	Hs
		228151 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH5_HUMAN (13-4644): 0: 3600: 21.81
+	Hs
		228369 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH8_HUMAN (121-4644): 0: 3555: 21.66
+	Hs
		227972 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH10_HUMAN (637-4644): 0: 3238: 25.24
+	Hs
		476122 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DYH7_HUMAN (749-4645): 0: 3499: 23.59
+	Hs
		227834 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DYH12_HUMAN (3846-4645): 0: 867: 21.83