HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32929329, 35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016607 - nuclear speck
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 530
+	Hs
		228995 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (41-425): 1.12e-60: 212: 17.81
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (41-435): 1.54e-59: 209: 17.08
+	Hs
		312605 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		227533 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		228332 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		161907 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		475757 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	At
		188090 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		U2A2A_ARATH (17-513): 1.44e-64: 221: 21.09
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		312642 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89
+	Hs
		161924 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (250-530): 7.68e-41: 158: 15.85
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (245-530): 5.7e-33: 135: 13.70