HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: I5P1 (Q14642)
Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)
Gene: INPP5A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 412
+	Mm
		88466 PRKN_MOUSE (1-465): 6.53e-131: 388: 83.66		D3Z656_MOUSE (7-394): 6.57e-69: 238: 15.31
+	Hs
		226647 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		I5P2_HUMAN (92-398): 1.33e-62: 219: 15.17
+	Hs
		227206 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		OCRL_HUMAN (77-400): 1.91e-56: 201: 18.58
+	Hs
		228249 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SHIP1_HUMAN (162-393): 2.45e-32: 131: 19.67
+	Hs
		228525 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		INP5K_HUMAN (161-401): 1.61e-17: 86: 17.06
+	At
		1092068 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		IP5P2_ARATH (161-394): 3.02e-59: 205: 18.75
+	Hs
		176358 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SHIP2_HUMAN (162-394): 2.48e-52: 190: 20.42
+	Dm
		1179001 Q9W418_DROME (1-77): 5.42e-30: 124: 32.47		Q7K161_DROME (1-398): 5.58e-54: 184: 15.52
+	Hs
		475170 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		INP5K_HUMAN (161-401): 1.61e-17: 86: 17.06