HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1233
+	Hs
		475763 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		226679 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62
+	Hs
		476584 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		475417 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62
+	Hs
		475291 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MYH1_HUMAN (563-1127): 7e-19: 95.6: 8.66