HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: NAA25 (Q14CX7)
N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)
Gene: NAA25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 972
+	Hs
		228574 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NAA15_HUMAN (10-524): 1.71e-127: 408: 12.39
+	Hs
		227777 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NAA16_HUMAN (10-527): 1.45e-106: 352: 11.11
+	Hs
		229192 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TF3C3_HUMAN (22-284): 5.84e-41: 164: 15.86
+	Hs
		174471 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		OGT1_HUMAN (21-375): 3.61e-17: 89.1: 14.80
+	Hs
		226620 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CDC27_HUMAN (41-260): 7.69e-13: 74.9: 10.91
+	Hs
		1219402 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		TF3C3_HUMAN (22-284): 5.84e-41: 164: 15.86
+	At
		95014 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		F4HS68_ARATH (10-625): 6.02e-88: 303: 14.17
+	Dm
		1180619 PRKN_DROME (1-463): 3.5e-106: 325: 42.19		Q7KJA9_DROME (21-375): 1.21e-16: 87.2: 15.03
+	Hs
		672859 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		CDC27_HUMAN (41-260): 7.69e-13: 74.9: 10.91
+	Dm
		284375 ARI2_DROME (228-464): 7.29e-69: 229: 20.92		Q7KJA9_DROME (21-375): 1.21e-16: 87.2: 15.03
+	Hs
		174509 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		OGT1_HUMAN (21-375): 3.61e-17: 89.1: 14.80
+	Hs
		476643 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		TF3C3_HUMAN (22-284): 5.84e-41: 164: 15.86
+	Hs
		672852 RN19B_HUMAN (220-460): 6.9e-59: 207: 19.18		CDC27_HUMAN (41-260): 7.69e-13: 74.9: 10.91
+	Hs
		174570 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OGT1_HUMAN (21-375): 3.61e-17: 89.1: 14.80
+	Hs
		475381 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CDC27_HUMAN (41-260): 7.69e-13: 74.9: 10.91