HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 4870
+	Hs
		227455 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ITPR2_HUMAN (4616-4856): 7.24e-99: 362: 32.29
+	Hs
		227819 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBP10_HUMAN (1010-1377): 6.97e-76: 269: 13.53
+	Hs
		228320 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RSPRY_HUMAN (970-1268): 3.87e-71: 253: 21.94
+	Hs
		228437 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RANB9_HUMAN (988-1377): 2.96e-69: 252: 13.03
+	Hs
		227608 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRL2_HUMAN (976-1265): 6.55e-49: 191: 18.24
+	Hs
		228217 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX1_HUMAN (1019-1233): 1.47e-43: 175: 17.35
+	Hs
		227742 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RN123_HUMAN (1071-1225): 2.34e-39: 164: 25.48
+	Hs
		1266160 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		DDX1_HUMAN (1019-1233): 1.47e-43: 175: 17.35
+	Hs
		476244 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RANB9_HUMAN (988-1377): 2.96e-69: 252: 13.03
+	Hs
		475902 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RN123_HUMAN (1071-1225): 2.34e-39: 164: 25.48