HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 915
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (258-583): 1.86e-38: 154: 11.21
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		198813 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RFOX2_HUMAN (301-501): 9.17e-31: 127: 21.80
+	Hs
		62521 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RFOX3_HUMAN (307-501): 3.08e-30: 124: 20.00
+	Hs
		228318 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP5_HUMAN (410-755): 3.8e-25: 110: 11.38
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (186-398): 4.59e-12: 71.7: 7.11
+	Hs
		1219380 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		SLTM_HUMAN (29-828): 1.63e-50: 195: 30.24
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		476448 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MDN1_HUMAN (63-707): 1.6e-64: 239: 11.64
+	Hs
		476581 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CE164_HUMAN (66-730): 4.88e-45: 178: 16.24
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	At
		98117 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		F4JNU3_ARATH (405-519): 1.1e-21: 96.1: 28.45
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (167-403): 2.69e-14: 79.1: 8.94
+	At
		981214 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		CP31A_ARATH (351-494): 6.41e-15: 79: 22.22