HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: F263 (Q16875)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 520
+	Hs
		226015 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		227603 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		241700 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		241674 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		226477 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PGAM1_HUMAN (244-442): 5.92e-72: 231: 20.88
+	Hs
		228354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PGAM5_HUMAN (215-426): 2.64e-51: 178: 17.05
+	Sc
		343501 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		PMG1_YEAST (248-421): 5.08e-55: 186: 21.40
+	Hs
		475305 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PGAM2_HUMAN (244-442): 1e-72: 233: 20.48