HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: DDX59 (Q5T1V6)
Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59) (Zinc finger HIT domain-containing protein 5)
Gene: DDX59

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 619
+	Hs
		228251 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX17_HUMAN (46-607): 8.82e-150: 451: 28.60
+	Hs
		226462 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX5_HUMAN (112-619): 6.59e-147: 440: 29.65
+	Hs
		133780 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX3X_HUMAN (32-610): 6.37e-144: 434: 26.79
+	Hs
		227955 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX42_HUMAN (30-605): 1.61e-139: 431: 29.47
+	Hs
		134115 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		DDX3X_HUMAN (32-610): 6.37e-144: 434: 26.79
+	Hs
		312636 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DDX17_HUMAN (46-607): 8.82e-150: 451: 28.60
+	Hs
		228549 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX23_HUMAN (185-579): 5.48e-74: 254: 35.42
+	Hs
		133805 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DDX3X_HUMAN (32-610): 6.37e-144: 434: 26.79
+	Hs
		227864 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX46_HUMAN (142-575): 2.19e-69: 244: 35.21
+	Hs
		229011 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DDX41_HUMAN (132-571): 1.69e-70: 241: 33.62
+	Hs
		476139 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		DDX17_HUMAN (46-607): 8.82e-150: 451: 28.60