HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: K2C79 (Q5XKE5)
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)
Gene: KRT79

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 535
+	Hs
		226692 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		226313 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C7_HUMAN (89-469): 7.05e-142: 419: 62.69
+	Hs
		226262 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		226160 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C75_HUMAN (3-535): 2.44e-90: 289: 57.27
+	Hs
		312501 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		226231 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C6B_HUMAN (1-481): 1.03e-76: 253: 60.64
+	Hs
		226397 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K2C5_HUMAN (3-460): 6.84e-75: 249: 63.51
+	Hs
		312447 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		227198 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		K22O_HUMAN (5-472): 5.28e-64: 222: 58.09
+	Hs
		312606 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		K2C72_HUMAN (23-522): 5.54e-77: 253: 55.36
+	Hs
		475775 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		K2C72_HUMAN (23-522): 5.54e-77: 253: 55.36