HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SCMC1 (Q6NUK1)
Mitochondrial adenyl nucleotide antiporter SLC25A24 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Short calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24)
Gene: SLC25A24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0034599 - cellular response to oxidative stress
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 477
+	Hs
		227774 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SCMC2_HUMAN (3-369): 1.25e-56: 196: 18.16
+	Hs
		229010 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2513_HUMAN (187-373): 1.59e-41: 159: 28.95
+	Hs
		226379 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT3_HUMAN (121-372): 7.14e-37: 139: 21.07
+	Hs
		226076 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		S2512_HUMAN (174-288): 6.05e-16: 82.4: 19.66
+	Hs
		226378 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT1_HUMAN (114-279): 1.4e-09: 61.2: 11.18
+	Hs
		226250 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADT2_HUMAN (114-278): 3.43e-09: 60: 10.65
+	Hs
		1317097 HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36		S2513_HUMAN (187-373): 1.59e-41: 159: 28.95
+	Hs
		476538 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		S2513_HUMAN (187-373): 1.59e-41: 159: 28.95