HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: KAT3 (Q6YP21)
Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III)
Gene: KYAT3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 454
+	Hs
		227593 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KAT1_HUMAN (42-452): 4.29e-119: 356: 51.57
+	Hs
		226198 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		AATM_HUMAN (9-432): 2.53e-98: 303: 15.44
+	Hs
		226453 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		AATC_HUMAN (34-440): 5.89e-89: 278: 13.16
+	At
		1092163 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GGT1_ARATH (14-452): 4.56e-93: 291: 14.80
+	At
		1092268 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		GGT2_ARATH (14-452): 1.23e-90: 285: 14.80
+	At
		1091980 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ISS1_ARATH (35-452): 9.21e-89: 277: 21.70