HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 902
+	Hs
		226328 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		228802 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAR11_HUMAN (604-893): 3.7e-90: 291: 28.62
+	Hs
		455013 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		476520 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PARP2_HUMAN (382-885): 1.99e-66: 235: 12.59
+	Hs
		475862 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PAR10_HUMAN (694-895): 4.97e-50: 193: 23.32