HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: LS14A (Q8ND56)
Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A)
Gene: LSM14A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 463
+	Hs
		123792 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPT5H_HUMAN (44-296): 9.53e-29: 121: 16.07
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (51-386): 1.86e-17: 87.7: 11.47
+	Hs
		226120 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SC31A_HUMAN (69-294): 1.26e-10: 66.1: 13.16
+	Hs
		228101 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KMT2C_HUMAN (45-386): 8.05e-10: 63.8: 12.25
+	Hs
		226957 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SC24C_HUMAN (106-353): 5.82e-09: 60.7: 10.08
+	Hs
		302333 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		SC31A_HUMAN (69-294): 1.26e-10: 66.1: 13.16
+	Hs
		302245 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SC31A_HUMAN (69-294): 1.26e-10: 66.1: 13.16
+	At
		1092229 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC24C_ARATH (79-368): 8.14e-11: 66.5: 8.67
+	At
		1092316 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC24A_ARATH (95-301): 1.56e-09: 62.3: 12.66
+	At
		1091778 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC31B_ARATH (70-253): 9.66e-09: 60: 10.88