HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 529
+	Hs
		226434 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CHIN_HUMAN (169-393): 9.36e-61: 208: 14.47
+	Hs
		227845 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RHG27_HUMAN (25-394): 2.41e-57: 207: 13.17
+	Hs
		49623 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RHG10_HUMAN (66-528): 1.13e-56: 204: 13.10
+	Hs
		228036 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RHG18_HUMAN (195-416): 1.91e-38: 151: 15.88
+	Hs
		73086 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		B4DXL2_HUMAN (269-419): 6.71e-26: 113: 18.54
+	Hs
		1135913 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		DEP1A_HUMAN (323-517): 3.25e-34: 139: 54.87
+	Dm
		1376600 Q9W418_DROME (1-77): 5.42e-30: 124: 32.47		RHGF_DROME (51-517): 3.9e-81: 275: 12.58