HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ASB15 (Q8WXK1)
Ankyrin repeat and SOCS box protein 15 (ASB-15)
Gene: ASB15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 588
+	Hs
		227310 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANK3_HUMAN (211-572): 4.93e-65: 233: 16.80
+	Hs
		228417 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ASB2_HUMAN (1-301): 2.38e-55: 199: 17.63
+	Hs
		229176 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ASB3_HUMAN (1-345): 1.63e-51: 186: 22.35
+	Hs
		227985 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ANKH1_HUMAN (2-114): 9.64e-17: 86.6: 11.50
+	Hs
		312683 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		ASB3_HUMAN (1-345): 1.63e-51: 186: 22.35
+	Hs
		476231 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ASB2_HUMAN (1-301): 2.38e-55: 199: 17.63
+	Hs
		476634 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ASB3_HUMAN (1-345): 1.63e-51: 186: 22.35
+	Hs
		476024 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ANKH1_HUMAN (2-114): 9.64e-17: 86.6: 11.50