HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 401
+	Hs
		227450 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		226572 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		228995 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		212082 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HTSF1_HUMAN (305-388): 4.02e-17: 85.4: 27.78
+	Hs
		312605 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		475757 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		312484 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	At
		188090 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		U2A2A_ARATH (244-398): 1.35e-29: 122: 22.54