HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: I12R2 (Q99665)
Interleukin-12 receptor subunit beta-2 (IL-12 receptor subunit beta-2) (IL-12R subunit beta-2) (IL-12R-beta-2) (IL-12RB2)
Gene: IL12RB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 862
+	Hs
		227729 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IL23R_HUMAN (31-328): 3.83e-80: 273: 23.49
+	Hs
		228210 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TITIN_HUMAN (9-349): 1.22e-09: 64.6: 8.60
+	Hs
		234546 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		DSCAM_HUMAN (2-836): 6.26e-23: 107: 7.43
+	Hs
		234457 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DSCAM_HUMAN (2-836): 6.26e-23: 107: 7.43
+	Hs
		475979 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SDK1_HUMAN (29-842): 1.75e-34: 145: 10.11
+	Hs
		476249 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CSF3R_HUMAN (363-861): 2.46e-20: 98.9: 10.52
+	Hs
		475473 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		LEPR_HUMAN (210-316): 6.47e-11: 68.3: 20.00