Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.39 1.00 0.625

The method score is based on:

Property Details
Experiments 25471590
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_1~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0007417 - central nervous system development
GO:0098793 - presynapse
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 465
Hs

1 347
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024